Brit. J. Anaesth. (1972), 44,841 EFFECT OF ETHER, TfflOPENTONE ANAESTHESIA AND SURGERY ON PLASMA THYROID-STIMULATING HORMONE (TSH) LEVELS IN MAN
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چکیده
The thyroxine responses to ether, thiopentone anaesthesia and surgical operation have been reported by some investigators (Fore, Kohler and Wynn, 1966; Oyama et al., 1969a, b). However, no study has been made to evaluate the influence of these anaesthetic agents and surgery on pituitary thyroidstimulating hormone (thyrotropin=TSH) in man. The synthesis and secretion of thyroxine in the thyroid gland are influenced by TSH. Therefore, it seems to be important to know whether anaesthesia and surgery influence thyroid function through the pituitary gland. Recently Oyama, Matsuki and Kudo (1972) demonstrated that neither halothane nor methoxyflurane anaesthesia influenced appreciably plasma TSH concentration. The present study was undertaken to investigate the effect of diethyl-ether, thiopentone and surgery on plasma TSH levels in man.
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